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  • CLINICALLY EVALUATED IN ECZEMA-PRONE SKIN & SCALP

Care that goes beyond 
basic moisturization.

MARIGOLD BIONATURALS is a clinically evaluated proprietary formulation for eczema-prone skin and scalp. It calms visible discomfort like itch, dryness, and redness, while supporting barrier repair, deep hydration, microbiome re-balance, long- term maintenance & management care.

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  • Clinically evaluated

  • Dermatologist Tested

  • Kids & adults

  • Steroid-free

  • Proprietary technology

PRODUCT · Launching soon

One formulation.
Multiple applications.

A clinically evaluated, steroid-free, microbiome & barrier support cream designed for the maintenance phase, the often overlooked space between acute treatment and basic moisturization. Supported by separate placebo-controlled clinical studies in atopic dermatitis (AD) and seborrheic dermatitis (SD).

Product
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FOR SENSITIVE, ECZEMA-PRONE SKIN & SCALP

MARIGOLD BIONATURALS™

A gentle, Microbiome + Barrier Support cream designed for skin that needs more than temporary relief.

🗸 Steroid-free

🗸 Leave-on care

🗸 Supports barrier repair

🗸 Deep hydration support

🗸 Adjunct support

🗸 Dermatologist-tested

🗸 Fragrance-free

🗸 Calms dryness, itch, redness + flaking

🗸 Supports a healthy skin and scalp microbiome

🗸 Maintenance & long-term management care

🗸 Daily Support

🗸  Safety evaluated in Kids + adults

APPLICATIONS

Targeted use for face + body + scalp + folds + sebum-rich areas.

Applications

MARIGOLD BIONATURALS™ has been clinically evaluated for both sensitive eczema-prone skin and flaky, irritation-prone scalp, using the same foundation.

Sensitive, eczema-prone skin

​For dryness, itch, redness, and barrier-stressed areas.​

Flaky, irritation-prone scalp 

For visible flaking, discomfort, and redness 

Folds + delicate areas

​For gentle leave-on support on crease-prone & sebum-rich skin folds.​

Apply a thin layer to clean, dry skin or scalp areas where dryness, itching, flaking, redness, or irritation tends to come back.

Use daily or as needed for targeted maintenance support on repeat-prone areas.

​

For scalp, part the hair and apply directly to the scalp. Massage gently until absorbed.

For external use only. Avoid contact with eyes.

CLINICAL EVIDENCE

Safety and performance evaluated in double-blind, randomized, placebo-controlled clinical studies.

Separate clinical studies were conducted in participants with mild to moderate atopic dermatitis and seborrheic dermatitis. Early improvement, continued benefits with regular use, and strong user response were observed across skin and scalp applications.

Clinically evaluated in kids and adults with mild to moderate AD

  • Comfort begins improving within 30 minutes

  • Supports hydration and overall skin-condition improvement over time

  • Shift toward a healthier skin microbiome observed

  • Strong user satisfaction reported with regular use

21%

itch comfort improvement in 30 minutes

57%

improvement in hydration

​

91%

improvement in overall skin condition score

76%

of users reported strong satisfaction

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Clinically evaluated in adults with mild to moderate SD

  • Clinical and biomarker signals supported improved skin comfort

  • Supports a healthier, more balanced scalp + skin microbiome

  • As scalp health improved, hair density and thickness showed encouraging signals

  • Follow-up suggested benefits continued even after regular use stopped

27%

itch comfort improvement in 30 minutes

​

31%

reduction in visible flaking

​​

​

28%

reduction in overall redness

 

​

100%

reported continued improvement and willingness to keep using

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THE SCIENCE

Feel stronger in your skin. 
Powered by microbiome science.

This formulation was designed around three connected ideas: skin microbiome re-balance, inactivated microbial components, and maintenance support over time

01

Skin Microbiome Re-balance

Healthy skin depends on balance across the microbiome, barrier and skin environment,the foundation this formulation is designed to support.

02

Proprietary technology

Developed through a patent-pending approach using food-derived lactobacilli, inactivated microbes, and their beneficial components.​

​Take Our Survey

If you or a loved one has experienced eczema, we would love to learn more about that journey. Your input will help us better understand real needs and experiences. Please take a moment to share your thoughts.

Get in touch with the Blossom Microbiotics team.

Contact

Affiliated with First Flight Venture Center
2 Davis Dr, Durham, NC 27709

We're a North Carolina-based biotechnology company developing science based & clinically evaluated dermocosmetics for long-term skin health.

© 2026 Blossom Microbiotics LLC. All rights reserved.

These formulations are dermocosmetic products and are not intended to diagnose, treat, cure, or prevent any disease.

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